{"id":35,"date":"2014-11-04T21:59:01","date_gmt":"2014-11-04T21:59:01","guid":{"rendered":"http:\/\/www.efolio.soton.ac.uk\/blog\/nde1n09\/?page_id=35"},"modified":"2014-11-04T21:59:01","modified_gmt":"2014-11-04T21:59:01","slug":"nanoparticles-and-regeneration","status":"publish","type":"page","link":"https:\/\/blog.soton.ac.uk\/evanslab\/nanoparticles-and-regeneration\/","title":{"rendered":"Nanoparticles and regeneration"},"content":{"rendered":"<p>When we are injured, suffer disease or get older, our organs and tissues become damaged and dysfunctional. To try and promote the regeneration of our tissues, we\u2019re trying to deliver drugs to specific cells in tissues called stem cells.<\/p>\n<p>We\u2019re doing this by designing tiny nanoparticles \u2013 just 1\/1000th the width of a single human hair in diameter \u2013 that can carry a variety of proteins and compounds. We know that a molecular pathway called the Wnt pathway is particularly important in controlling how stem cells divide and differentiate. However, the same pathway can have potentially detrimental effects on other cell types.<\/p>\n<p>To make sure that molecules and drugs are carried only to stem cells, we are \u2018tagging\u2019 our drug carriers with molecular flags that are only recognised and taken up by specific cell types. Ultimately we hope that this technology can be used to treat injury and degenerative disease in bones and the skin.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>When we are injured, suffer disease or get older, our organs and tissues become damaged and dysfunctional. To try and promote the regeneration of our tissues, we\u2019re trying to deliver drugs to specific cells in tissues called stem cells. We\u2019re &hellip; <a href=\"https:\/\/blog.soton.ac.uk\/evanslab\/nanoparticles-and-regeneration\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":78457,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-35","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blog.soton.ac.uk\/evanslab\/wp-json\/wp\/v2\/pages\/35","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blog.soton.ac.uk\/evanslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blog.soton.ac.uk\/evanslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blog.soton.ac.uk\/evanslab\/wp-json\/wp\/v2\/users\/78457"}],"replies":[{"embeddable":true,"href":"https:\/\/blog.soton.ac.uk\/evanslab\/wp-json\/wp\/v2\/comments?post=35"}],"version-history":[{"count":0,"href":"https:\/\/blog.soton.ac.uk\/evanslab\/wp-json\/wp\/v2\/pages\/35\/revisions"}],"wp:attachment":[{"href":"https:\/\/blog.soton.ac.uk\/evanslab\/wp-json\/wp\/v2\/media?parent=35"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}